Gold(III) chloride catalysed synthesis of 5-alkylidene-dihydrothiazoles.
نویسندگان
چکیده
A two step synthesis of dihydrothiazoles is presented. First, the previously unknown N-propargylic dithiocarboimidates are produced in good yields from easily available, cheap starting materials. The subsequent gold catalysed ring closure is fast and efficient, leading to dihydrothiazoles through a cascade of 5-exo-dig cyclisation and 1,3-alkyl migration. The yields range from 74% to 95%.
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عنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 13 شماره
صفحات -
تاریخ انتشار 2011